Endocrine Abstracts

A 38 year old woman was admitted with three day history of right sided chest pain, right upper abdominal pain and vomiting. She has anti-phospholipid syndrome (APS) treated with long term lower molecular weight heparin (Dalteparin) for inferior vena cava thrombosis. On presentation, she was hemodynamically stable with haemoglobin of 154 g/l, CRP 170 mg/l, white cell count 15×109/l, platelet of 90×109/l and sodium of 136 mmol/l. CXR showed consol...

Grave’s disease is an auto-immune disorder which responds well to medication and up to half of the patients who take anti-thyroid drugs go into remission. We present a patient with Graves’ disease, who developed acute hepatitis associated with Carbimazole and, re-challenged with Carbimazole when she represented with in fast atrial fibrillation (AF) with relapse of hepatitis. A 75 year-old lady admitted with palpitation and chest tightness. She had a background of par...

Introduction and aim: In the UK, 15% of couples are affected by infertility which is due to primary or secondary male factors in 30%. Induction of spermatogenesis with gonadotrophins is a long established endocrine treatment for gonadotrophin deficiency. However, there are concerns that some patient groups have very low success rates. The aim of our audit was to define success of spermatogenesis and fertility rates amongst these men.Methods: We retrospec...

We present the case of a 53 year old gentleman with recurrent bladder paraganglioma. He presented initially in 2010 with headache and blurred vision when passing urine. The tumour was surgically removed, BP normalized and his postoperative MIBG-scan was normal. The patient presented with hypertensive crisis 4 years later with a suspicion of tumor recurrence, confirmed biochemically and radiologically. Treatment with phenoxybenzamine and bisoprolol resulted in adequate BP contr...

Adrenal insufficiency is serious, life-threatening condition. Classical features include nausea, malaise, weight loss and hypotension. It is usually diagnosed at a late stage only when it presents as adrenal crisis. We report a patient with autoimmune adrenal insufficiency who presented with chronic hyponatremia and a repeatedly normal serum cortisol level. A 66-year-old female was referred to endocrinology with a 12-month history of hyponatraemia (Na 125–131 mmol/l). She...